Graviola is an Amazonian rainforest herb that has been used in alternative cancer clinics for over 25 years, and likely due to its word of mouth success, it has been investigated by such organizations as the National Cancer Institute and the National Institutes of Health.


Graviola is a small tree with large dark green leaves which produces a fruit the size of a large cantaloupe with a delicious white flesh. The leaf of the Graviola tree has been proven to have unique properties that assist the immune system in cleaning abnormal tissue growth. Various research, including studies conducted by the National Cancer Institute, reveals that it contains natural compounds shown to have exceptional cytotoxic activity, meaning prevention of abnormal cellular division. 1

A set of phytochemicals called annonaceous acetogenins which may be unique to this plant have been documented, and in fact patented as anti-tumor agents. Purdue University, in conjunction with the National Institute of health, has filed at least nine patents on their work surrounding antitumorous and antimicrobial uses of these acetogenins.

One study demonstrated that an acetogenin in Graviola has 10,000 times the potency of Adriamycin (a chemotherapy drug). Reportedly, it only seeks out the abnormal cells and destroys them, leaving the healthy cells. 2


Graviola may prove to be beneficial for a wide array of ailments. Around the world Graviola has a long history of use for the following:


  • The indigenous people of the Amazon use the fruit and seeds for intestinal health, including the elimination of parasites and for stomach and bowel discomfort.
  • Teas are prepared from the root and used as a calming nerve tonic and to help maintain healthy glucose levels.
  • In the Peruvian Amazon the bark, roots, and leaves are used for diabetes and as a sedative and antispasmodic.
  • In the Brazilian Amazon, a leaf tea is used for liver problems, and the oil of the leaves and unripe fruit is mixed with olive oil and used externally for neuralgia, rheumatism, and arthritis pain.
  • In other parts of the world, such as the Polynesian Islands, Graviola tea is consumed daily, much like the Chinese drink green tea, to elevate mood and increase quality of life.


Aside from its medicinal use, Graviola fruit is eaten regularly throughout South America as a delicious and refreshing fruit during a hot summer day.



Note: No drug interactions have been reported



  • Graviola has cardio-depressant, vasodilator, and hypotensive (blood pressure lowering) actions.
  • Extremely large doses may cause nausea and vomiting.
  • Avoid combining with ATP enhancers such as Co-Q10.
  • Long term use may destroy friendly intestinal bacteria.
  • If used for more than 30 days, a high potency vitamin such as Maximum International’s Maxi Man or Lady Max is recommended.
  • Do not use during pregnancy.





  1. Unpublished Data, National Cancer Institute. Anon: Nat Cancer Inst Central Files - (1976) from Napralert Files, University of Illinois, 1995
  2. N.H. Oberlies and J.L. McLaughlin, "Use of Annonaceous Acetogenins to Treat Multidrug Resistant Tumors," disclosed to Purdue Research Foundation, February 17, 1997, P-97020.00.U.S.

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